Raj Kumar Sen, Priyanka Prabhakar, Neha Bisht, Monika Patel, Shruti Mishra, Amit K. Yadav, Divya V. Venu, Gaurav Kumar Gupta, Pratima R. Solanki, Seeram Ramakrishnan, D.P. Mondal, Avanish Kumar Srivastava, Neeraj Dwivedi* and Chetna Dhand* Pages 5815 - 5849 ( 35 )
Current advances in constructing functional nanomaterials and elegantly designed nanostructures have opened up new possibilities for the fabrication of viable field biosensors. Two-dimensional materials (2DMs) have fascinated much attention due to their chemical, optical, physicochemical, and electronic properties. They are ultrathin nanomaterials with unique properties such as high surface-to-volume ratio, surface charge, shape, high anisotropy, and adjustable chemical functionality. 2DMs such as graphene-based 2D materials, Silicate clays, layered double hydroxides (LDHs), MXenes, transition metal dichalcogenides (TMDs), and transition metal oxides (TMOs) offer intensified physicochemical and biological functionality and have proven to be very promising candidates for biological applications and technologies. 2DMs have a multivalent structure that can easily bind to single-stranded DNA/RNA (aptamers) through covalent, non-covalent, hydrogen bond, and π-stacking interactions, whereas aptamers have a small size, excellent chemical stability, and low immunogenicity with high affinity and specificity. This review discussed the potential of various 2D material-based aptasensor for diagnostic applications, e.g., protein detection, environmental monitoring, pathogens detection, etc.
Aptamer, biosensor, 2D material, mxene, graphene, diagnosis.
CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, Special Centre for Nanoscience, Jawaharlal Nehru University, New Delhi 110067, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, Special Centre for Nanoscience, Jawaharlal Nehru University, New Delhi 110067, Center for Nanofibers and Nanotechnology, Department of Mechanical Engineering, Faculty of Engineering, 2 Engineering Drive 3, National University of Singapore, Singapore, 117576, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, CSIR-Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal