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Review Article

Multi-Component Methodologies in Solid-Phase Organic Synthesis

[ Vol. 6 , Issue. 3 ]

Author(s):

Scott L. Dax*, James J. McNally and Mark A. Youngman   Pages 255 - 270 ( 16 )

Abstract:


Solid-phase organic synthesis, particularly when used in conjunction with combinatorial techniques, is emerging as a revolutionary technology in chemistry. MultiĀ­ component reaction systems are particularly valued because several elements of diversity can be introduced in a single transformation thereby expanding the diversity of compound libraries. A variety of multi-component reactions have been successfully adapted for solid-phase technology as described in this review.

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