Kenji Nishioka, John McMurray, Fahad AI Obeidi and B. Montgomery Pettitt* Pages 153 - 166 ( 14 )
We have reviewed aspects of the medicinal chemistry of Tuftsin. Biochemical and clinical aspects including physioogy and assays are briefly accounted for. Structure-activity relationships found in the literature provide a link between the synthetic/design strategies and the biological response. Directed rational design and synthetic techniques are reviewed for both tuftsin and its analogs.