Yaqi Hu, Yifan Zhang, Shuwen Wang, Rui Wang, Qi Yuan, Leiqi Zhu, Fangqi Xia, Mengzhen Xue, Yaqi Wang, Yuanyang Li and Chengfu Yuan* Pages 678 - 687 ( 10 )
Long intergenic noncoding RNAs (lincRNAs) have a variety of properties that differ from those of messenger RNAs (mRNAs) encoding proteins. Long intergenic nonprotein coding RNA 667 (LINC00667) is a non-coding transcript located on chromosome 18p11.31. Recently, many studies have found that LINC00667 can enhance the progression of various cancers and play a key part in a lot of diseases, such as tumorigenesis. Therefore, LINC00667 can be recognized as a potential biomarker and therapeutic target. So, we reviewed the biological functions, relevant mechanisms, as well as clinical significance of LINC00667 in several human cancers in detail.
LINC00667, long intergenic noncoding RNAs (lincRNAs), cancers, cell functions, messenger RNAs, protein coding.