M. Gary-Bobo, O. Vaillant, M. Maynadier, I. Basile, A. Gallud, K. El Cheikh, E. Bouffard, A. Morere, X. Rebillard, P. Puche, P. Nirde and M. Garcia Pages 1946 - 1955 ( 10 )
In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods for non invasive therapies. Here we detail the necessity of a synergy between passive and active targeting for an actual specificity of cancer cells.
Cancer, multiple targeting, nanoparticles, non-invasive therapies
, , , , , , , , , , , Institut des Biomolecules Max Mousseron, UMR 5247 CNRS-UM1-UM2, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 05, France.