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Syntheses of Hydroxylated Cyclic β-Amino Acid Derivatives

[ Vol. 12 , Issue. 26 ]

Author(s):

Marta Palko, Lorand Kiss and Ferenc Fulop   Pages 3063 - 3083 ( 21 )

Abstract:


This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

Keywords:

β-amino acids,peptides,asymmetric synthesis,selective functionalization

Affiliation:

, , Institute of Pharmaceutical Chemistry, University of Szeged, H-6701 Szeged, POB 121, Hungary.



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