Stephen J. Shuttleworth, Richard V. Connors, Jiasheng Fu, Jinqian Liu, Mike E. Lizarzaburu, Wei Qiu, Rajiv Sharma, Malgorzata Wanska and Alex J. Zhang Pages 1239 - 1281 ( 43 )
This review chronicles original literature dating back to 1992 outlining the applications of parallel synthesis and combinatorial chemistry to the synthesis of compound libraries focused towards specific superfamilies of molecular targets. Target families that have received significant literature coverage include kinases, proteases, nuclear hormone receptors and cell surface receptors, notably GPCRs.
parallel,combinatorial,gpcr,protease,kinase,nuclear hormone receptor
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